The ban by US regulators on Wednesday in food items comes more than three decades after the additive was barred from cosmetics.

The United States has banned the use of a synthetic food dye that gives some candies, cakes and certain oral medications a cherry-red colour, following evidence that the dye causes cancer in laboratory rats.

The ban on Wednesday by the Food and Drug Administration on the Red No. 3 dye in food items comes more than three decades after it was barred in cosmetics.

“Why you would say something can’t be in cosmetics, but you can eat it makes no sense to me. I am very pleased that they finally have done what I think they should have done years ago,” said petitioner Linda Birnbaum, former director at the National Institute of Environmental Health Sciences and National Toxicology Program.

Consumer advocacy groups have been pushing for the dye’s ban for several years, including a petition in 2022 to review studies that show high exposure to the additive may cause cancer in male rats.

“The FDA cannot authorise a food additive or colour additive if it has been found to cause cancer in humans or animals,” said Jim Jones, deputy commissioner for Human Foods at the US Food and Drug Administration (FDA).

The regulator, however, said studies in other animals and in humans did not show these effects and that available evidence does not support claims that the dye’s use in food and oral drugs puts people at risk.

Manufacturers who use Red No. 3 in food have until January 15, 2027, to reformulate their products and ingested-drug makers have until January 18, 2028, to comply with the ban.

Lawmakers had grilled FDA Commissioner Robert Califf in a recent US Senate committee hearing over the use of food dyes.

“Food safety is the number-one priority for US confectionery companies, and we will continue to follow and comply with FDA’s guidance and safety standards,” the trade group the National Confectioners Association said.

Robert F Kennedy Jr, US President-elect Donald Trump’s choice to lead the country’s top health agency, has frequently talked about reducing chemicals in food.